Hi TAC,
I will take a crack at this question.
In an extreme case, everything can be damaged.
The case I have in mind when saying this follows.
If the current should suddenly (i.e. < 1ns) increase to say 100 Amps (this is larger than 20mA) you must take into concideration the effects of the RF response of the various devices (ever hear of an EMP weapon?). In the simplest case, let us concentrate on just the ground paths. At RF frequecies the wires must be analyzed as transmision lines. Depending on the diferences in wave propogation due to the difference in length and the materials used, there may be some very large potential differences in the what we normal concider ground planes ( put a gold embosed coffee cup in an old microwave and watch what happens)
. I think you figure out where I am going with this.
So, if you will buy this arguement that everything is suspect under the these extreme conditions, and we recall that nothing should be suspect when everything is within spec, then there may be some threshold in-between these cases where the reliability drops off. Where that point is I cannot specify without all the details.
In closing, I would like to invoke a variation on an old quote;
"There are only two types of electronic devices in the world,
those that are bad,
and
those that are not bad yet".
Trying to help,
Ben