Hi,
you must use functions from "Functions->Instrument I/O->Serial" palette.
The idea is to do the next steps:
1.Open serial VISA session with specified COM port parameters.
2.Read specified number of data bytes from COM port.
3.Convert data from string format to array of I32 words with the help of "Functions->Advanced->Data Manipulations->Type Cast.vi"
4.Close VISA session.
The example is attached.
Also you may take a look at built-in LV examples.
Select from LV menu the next item:
"Help->Examples...->I/O Interfaces->Serial Communication->........."
Good luck.
Oleg Chutko.