Hello Van,
Can you elaborate a little more on your application? What is the requirement for having more than 65,534 bytes of buffer size? Can you not read data in smaller chunks at a time and then write to a file (or similar approach)?
Also, in the more recent versions of LabVIEW, serial vis are replaced by VISA vis, and thus is the provision of 'VISA Set I/O Buffer Size.vi' to be able to reset the size of buffer (which goes upto around the same number that you have mentioned above-65KBytes). Please let know.
Again, thank you for choosing National Instruments!
Swapnil P.
National Instruments Engineer