your baudrate is the speed on the serial line and overrun occcurs in your pc
your simply not reading fast enough and taking the highes possible baudrate makes it worse.
In your main vi you need two loops (running in parallel)
in one read reaad all seril ports one by one and dump the data in an action engine (see link below on action engines)
http://forums.ni.com/ni/board/message?board.id=170&message.id=240328
In the other loop read from the action engine and process the data.
good luck
greetings from the Netherlands