There should no little problem with this as communication with modems can be handled like any other serial communication. You can use either the traditional serial communication vi's or NI-VISA (recommended). When you open the serial port/session you'll have to use the serial communication settings of the modem, which is not the same as the communication/connection rate of the modem (57.6k for example). To communicate with the modem, you can use the AT commands - though your modem may have specific (non-standard) commands and serial/VISA write and read.