Yes you can get the command-line args, but this only works when first launching the application. It will not work if the application is already running. For this, you need to message into the running application using some other mechanism. Most apps use DDE for this.
Here is a utility that will allow you to get the command-line arguments using a WinAPI call:
http://www.openg.org/tiki/tiki-index.php?page=Command Line Arguments
Also, if you are using LabVIEW 7.0 you can get the command-line arg's using the VI Server property "App::Command Line Arguments".
-Jim