Hello,
A few things come to mind:
1. I wonder if the excel version matters here. Could it be that you have a different version of the activeX control on your target machine?
2. Posting a minimal, simplified version of your code may help as well... so we can see precisely where the error occurs. Maybe just the open operation and if relevant the ActiveX property node from which you are receiving the error - identifying precisely where the error originates will be helpful.
3. Here is another thread addressing the same error that may be helpful to you:
http://forums.ni.com/ni/board/message?board.id=170&message.id=172065
Give it a thorough read just to make sure you're not having a similar issue - if you are, you just may have the solution!
I hope this helps!
JLS