Figured it out by myself. The default state of the RS485 transmitter is set in the Windows Registry. See the following; (TranscieverMode determines the default mode of the RS485 transmitter) Someone apparently had monkeyed with the Registry on one of my PCs...
[HKEY_LOCAL_MACHINE\SYSTEM\ControlSet001\Enum\MF\PCI#VEN_1093&DEV_70ED&SUBSYS_70ED1093&REV_00\a&14910dbd&0&786068686848F0#Child0003\Device Parameters]
"PortName"="COM11"
"PollingPeriod"=dword:00000000
"NIPortNumber"="Port1"
"DceSupported"=dword:00000000
"ForceFifoEnable"=dword:00000001
"BiasEnabled"=dword:ffffffff
"BiasLevel"=dword:ffffffff
"SerialNumber"=dword:0122f0e6
"IoManagementScheme"="DMA"
"InterruptManagementScheme"="Mailbox"
"ResourceWindowType"="Memory"
"ResourceWindowOccurrence"=dword:00000000
"IoBridgeType"="MiniMite"
"SerialControllerType"="Oxford16c954"
"FifoRxMin"=dword:00000001
"FifoRxMax"=dword:0000007f
"FifoRxDefault"=dword:00000040
"RxFIFO"=dword:00000040
"FifoTxMin"=dword:00000001
"FifoTxMax"=dword:00000080
"FifoTxDefault"=dword:00000080
"TxFIFO"=dword:00000080
"ClockFrequency"=dword:03840000
"BusType"="PXI"
"Series"="8433"
"Standard"="RS-485"
"TransceiverMode"=dword:00000083
"MaxBaudRate"=dword:002dc6c0
"Isolation"="1"
"NumberOfPorts"=dword:00000004
"MAX_Name"="PXI-8433/4"
"ResourceWindowOffset"=dword:00000800