Hi Jason,
Sometimes getting the signal connections right can appear to be a bit of a tricky process, but once everything is accounted for it tends to be pretty easy.
If you want to learn more about how to properly reference all of your measurements then take a look at these documents.
Why Do My Analog Inputs Seem To Float?Field Wiring and Noise Considerations for Analog SignalsFrom what you mentioned in your comments it looks like you are trying to read a differential measurement from a photodiode. If that's the case you may want to connect your photodiode to AI 0 and AI 8. Then take your differential measurement of the photodiode.
However, you mentioned that you were doing everything in in RSE. If that's the case, then for your RSE measurement you should connect the positive terminal to AI 0 (pin 68) and the negative terminal of the photodiode to AIGND (pin 67). Make sure that you have your board set for a RSE measurement too. The easiest way to do that is in the configuration panel when you create a task in Measurement and Automation Explorere (MAX) or in the Create Virtual Channel.vi when using LabVIEW.
What I think is happening in your case is that the board may not be configured properly so it is causing the board to saturate and that's why it looks like your measurements are railing.
You also mentioned that you wanted to know what a good size for your Bias Resistors would be. If you were able to look at the above links, then you should find that typical values for a Bias Resistor are in the range of 10 kOhms to 100 kOhms.
Best of luck getting your measurements back to normal!
Regards,