You can use either VISA or the older serial functions.
Both of them interface to the serial port of your computer. VISA is an API that works with not only serial instruments, but also GPIB, VXI, and TCP/IP. The theory behind VISA is that a single driver can be used for an instrument no matter how it's connected to the computer. The fact that your instrument is old should have no bearing on whether you use VISA or not. VISA does require more files (and larger) to be installed on the computer whereas the old serial drivr requires only one small one (serpdrv). This can be a factor if you build an application and want to distribute it. NI is no longer supporting the old serial drivers and there has been some recent speculation about whether they will be pa
rt of future LabVIEW releases. I almost always use VISA but then I almost always have GPIB instruments mixed with my serial ones and I have to install VISA anyway. In your application, since you just want to write to the instrument, all you need are two functions. Use the VISA Configure Serial Port (check the name, I'm not on a computer with LabVIEW right now) where you specify the baud rate, etc., and then a VISA Write with the command you went to send as the write string. To the VISA configure, you can create a constant or front panel VISA Resource Name. Click on it to select Com1. Connect the VISA REsource Out of the configure to the VISA Resource In of the VISA Write. Do the same with the Error Out/Error In, create an Error Out indicator from the VISA Write to check if any errors occurred and you're done.