There are other ways to do this other than ActiveX. It all depends on what you want. Although you cannot read and interpret excel files directly without ActiveX, you can save your excel worksheet as a tab delimited text file you can use the "Read From Spreadsheet File VI" to read this type of file. The output of this VI will be a 2-D array of your spreadsheet data. You can then index a row from this array and do your manipulation.