You've got several options. There is a shipping example that uses DDE to talk to an Access database. DDE sucks so you probably don't want to do that. There is ActiveX. There have been a lot of examples posted to the forum so you might want to do a search. ActiveX can be a real pain though. The nicest solution is to buy the Database Connectivity Toolkit from NI. It uses ADO/SQL to communicate to any database and hides a lot of complexity of learning SQL. There is also the free open source toolkit called LabSQL from
Jeffrey Travis. This uses ADO/SQL to talk to any database. You'll need to learn SQL but that's not really that big a task.