Hello,
Looking at your program, it appears that you have the Vision module. I would think that you could accomplish this application by performing a pattern match using the cross (and some of the blank space around it) as a target, and then after finding it, perform the overlay functions to create your box. Note that the boxes will be individual entities and will not lay perfectly on top of eachother as they have in your image unless the crosses are exactly 50 pixels apart.
When you use the overlay function to create the box, you should base the location of the start and endpoints on the found pattern match.
Note that if you are using Vision 7 or 7.1, Vision Assistant should be able to aid you in setting up the pattern match. It will make creating the template, matching the pattern and generating the Labview code very easy. Give it a try!
Hope this helps,
Robert