You need to install the VISA run-time. If you are just using VISA for serial communication, then there is an option on the app builder (Installer Settings>Advanced) for Serial Port Support. This will add a much smaller version of the VISA run-time engine to the installer you create. If you are using GPIB, etc., you have to install the hardware driver (i.e. NI-GPIB) and the full VISA run-time engine.