Student Projects

Showing results for 
Search instead for 
Did you mean: 

Frequency-Domain Optical Coherence Tomography (FD-OCT)

Please complete the following information

Contact Information

University and Department:      School of Life Sciences and Biotechnology, Shanghai Jiao Tong University

Team Members:                      Xiaowei Wu, Tobias Braeuler, Cuixia Dai, Peng Xi, Chuanqing Zhou, Qiushi Ren

Faculty Advisors:                      Peng Xi

Primary Email Address:  

Primary Telephone Number (include area and country code):    +86 21 3420 4076

Project Information

Project Title:          Frequency-Domain Optical Coherence Tomography (FD-OCT)

List all parts (hardware, software, etc.) you used to design and complete your project:


NI IMAQ PCI-1428 image acquisition card

LabVIEW 8.5

Describe the challenge your project is trying to solve.

OCT is a high-resolution optical cross-sectional imaging technology. We need to develop a FD-OCT system for the imaging of the retina of the human eye.

      In our experiment, the following challenges need to be solved:

    (1)  a constant timing clock for each galvanometric scanning.

    (2)  Two voltage signals to drive the galvanometer pair and continuous galvanometric scanning driving;

    (3)  Synchronization with the line-CCD camera;

    (4)  Post-processing of the interferogram for visualization;

    (5)  A user-friendly GUI for easy operation of the system.

Describe how you addressed the challenge through your project.

In our system, a FD-OCT is constructed for the imaging of the retina of the human eye. (Fig.1)

A broad band light sources beam is employed as the low coherent light source. The incidence was split in a fiber coupler and focused on the background of the eye and on a reference mirror, respectively. The reflected beams are recombined in the fiber coupler and interfere there, coding the information of the retina in the interferogram. Afterwards, the interferogram is recorded by a grating-based spectrometer. The spectrometric data was taken with a line CCD camera (Aviiva e2V). Together with NI IMAQ PCI-1428 image acquisition card, the data for each A-scan is recorded and then processed for visualization by a custom-designed program written with Labview.

Each shot gives us on depth scan (A-scan) of the eye, with two galvanometric scanning mirrors the beam is scanned across the surface of the retina to record A-scans at different positions to reconstruct the 3-D morphological structure of the retina in vivo (Fig. 2).

At several core parts of our system, NI products are used:

l  First of all, the scanning mirror in the galvanometer are driven and controlled by a NI PCI 6731 data acquisition card, allowing an easy to control and precise beam positioning.

l  The intferogram, recorded by a line-scan CCD camera, is transferred to the PC by use of the NI IMAQ PCI 1428 image acquisition card, allowing an exact triggering and fast image transfer.

l  The mirror in the reference arm is mounted on a motorized actuator stage, making fine adjustment of the mirror position possible. The stages motion controller is connected to a NI PCI-GBIP card.

All of these parts are controlled by NI Labview 8.5. The post processing is also done with Labview. Furthermore, we also designed a Labview based, custom made, graphical user interface, allowing an easy access to the system and suiting the demands of medical professionals. (Fig.3)

Please upload photos below:

Fig 1.JPG

Fig. 1  Diagram of the FD_OCT system.

Fig 2.JPG

Fig. 2  Our OCT imaging result revealed the biological structures of the human retina.

Fig 3.jpg

Fig. 3  The FD-OCT GUI.

Please insert video below:

[Click on video icon on task bar]