Hello,
The PXI-4472 has a antialias filter which limits the bandwidth of the signal it can represent. The SCXI-1125 has +-300 Vrms of working isolation per channel. The information regarding the PXI-4472 filters and the SCXI isolation specifications may be found at
NI Product Manuals.
Let me know if you have any further questions. For direct questions regarding the PXI-4472, you will be better off posting a new question to the DSA discussion forum.
Best Regards,
Jared A