Hello,
No. All LabVIEW functions are disable in Safe Mode. However, you can still reboot the controller from Measurement & Automation Explorer. Please reference pag 4-7 in the user manual for additional information: http://digital.ni.com/manuals.nsf/websearch/F039F11F361A6C8D86256BE9007A8E57?OpenDocument&node=132100_US
Regards,
Bill Boldt
Applications Engineer
National Instruments