In order to help us troubleshoot your problem, it is important to mention the hardware/software you are using.
There is a great KnowledgeBase entry that discusses the -10846 error and possible resolutions at:
http://digital.ni.com/public.nsf/3efedde4322fef19862567740067f3cc/75bf35eb4afb834f862566210065fa61?OpenDocument
This entry could be found by going to www.ni.com, clicking on the KnowledgeBase link, and searching for "10846."