I was able to update to Windows 10 an PXIe-8133 and PXIe-8135. It was straightforward.
The trick was to start with Windows 7 working on the module (HAS to be 64 bits version), and then updating to Windows 10.
I started one module with original installation on Win 7 and the other had 32bit version, so I installed a fresh Win 7 64bit, updated with the updater bought on eBay, and both unit have been resold to a customer of mine. Very Happy indeed from getting these two devices in Windows 10 v1909 for a very cheap price.
One for the team!
I just upgraded my NI PXIe-8135 controller to Windows 10 Pro 21H2 (from a MediaCreationTool ISO on a bootable USB stick), and it all worked fine. I didn't need the old Windows 7 additional driver package that NI provides at https://www.ni.com/en-gb/support/downloads/software-products/download.pxie-8135-firmware-and-additio... because Windows 10 already comes with almost all the required drivers.
There were only two unknown devices listed in the Device Manager after I had also installed the usual NI PXI Platform Support package, NI 488.2 GPIB driver, and the drivers for all my PXIe modular instruments. One was a "NIC7019 Trigger Router" for which there is a Windows 10 compatible driver available at https://knowledge.ni.com/KnowledgeArticleDetails?id=kA00Z0000015AWVSA2&l=en-GB and the other was for an "Intel Management Engine interface", for which Windows Update offered me a suitable driver as an optional update. (NI's Windows 7 additional drivers ZIP would also have had an older version of that Intel driver.)
So so far the only reason that I can think of why the NI PXIe-8135 might not be officially supported for Windows 10 is that Intel says that their Ivy Bridge generation of CPUs is supported for Windows 10 only for updates: https://www.intel.com/content/www/us/en/support/articles/000006105/processors.html