Alarms, Events, and logging to historical database for hyper trends make the database folder too big too fast.
Try a cleaning of the events and alarms (or avoid as much as possible unnecessary events and alarm records). Try also to create the database folder out of Lookout folder (i.e C:\Data).
Detaching, deleting, and creating databases can create fragmentation of the Hard Drive with the time as well. As a tumb rule, keep checking if the hard drive is asking for a defragmentation and how big is the database once in a while. I had that before......
Good luck this time......