How long is the RS232???? The longer the cable, the more capacitance to ground, the lower the frequencies (baud) it can handle. Also, the longer the run, the more RF it can pickup.
Is it shielded? Is it grounded?
Is it running near any power conduits (110VAC, 220Vac, 480vac, ETC.)? Or worse, in a power conduit?
Regards,
Tommy Scharmann