+/-
10V Card w/ 16 bit resolution means
20V
/ 216 = 0.000305V resolution
So if we have a 10 lbf sensor with a +/- 10 V. 1.0 lbf for every volt times the resolution of your card and the best resolution would be 0.000305 lbf
And if we have a 5 lbf sensor with a +/- 10 V. 0.5 lbf for every volt times the resolution of your card and the best resolution would be 0.0001525 lbf
The amplifier that you used will have to be added for error in this calculations. If you have a zero to ten volt signal then the resolution will also change. Afer calibration the resolution will change slightly as well.
Hope this give you enough info that you can figure out the rest.
Tim
GHSP