DeeJay,
This is probably best answered by some Windows/VC++/VB people. This is a system question. What you need to find out is what dll to call, and what function to call within that dll. I have, somewhere, a function that reads the mouse position (it's also on this site somewhere) and I am sure that the same dll (win32.dll???) is the one to call, but I don't know the function to call or how to set the function to disable the mouse.
Search for a Visual Basic users group, or just search MSDN for your question. If you find the answer, be sure to share it with us here.
Thanks, and good luck