Shijun,
If you do not require any timing for your digital I/O (just doing software-timed reads and writes to the lines), then yes, you can use those control lines as inputs and/or outputs. Again, this is unstrobed I/O, where you do not plan on doing any handshaking or pattern generation (input or output a pattern based on a clock signal). You can find information in the 653x User Manual in Chapter 2. Look in the section entitled "Using Control Lines as Extra Unstrobed Data Lines". There is a table describing which control lines are input and which are output, and there are some flow charts describing how to do it in your program. The manual is available at the http://www.ni.com/support pages.
Regards,
Geneva L.
Applications Engineer
National Instruments