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VISA is a high level API that generally doesn't access hardware directly. For most of iit's interfaces DMA doesn't even come into play from the point of view of VISA (Serial, GPIB, TCP/IP, etc). The only exception to that might be the PCI register level access but DMA support there would be a real pain. Generally the only way to support something such as DMA in a useful way is to do it in a kernel driver directly. Anything else is more likely causing more trouble than you ever would want to encounter.