You might not have the proper VISA Server security settings. This would mean that you can change the properties in side the VI, but you wouldn't be able to change the in MAX. Open MAX, go-to Remote Systems, select your RT System, then Software and finally click on the NI-VISA 3.3 folder. Select the VISA Options tab on the bottom and then select the Security item under VISA Server. You will need to make sure that the IP of your host machine (the one you are doing this from) is located on this list. To add an IP address to the list Click Add, then type in the IP and then click in the blank area inside the box. You should then get the Save option at the top. Make sure you click save. In addition, you can use wild card characters to specify the IP. For example I add something like 12.3.55.* so any computer on my local subnet can access the device and I have noticed that my computer will sometimes change IP addresses.
One other thing that I would suggest is making sure you have the latest NI-Serial RT driver installed. This requires upgrading to at least
NI-VISA 3.3 and then downloading the latest NI-Serial driver for RT which can be found at
ftp://ftp.ni.com/support/ind_comm/serial/lvrt/. Copy the MSI file to your computer and run it. You will also need to install the new software to each RT Target. Note that currently the latest NI-Serial 2.5.5 will still display NI-Serial 2.5.4 on the monitor if you have one connected to your RT target.
I hope this helps out.
-Josh